ldha inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15362	FX-11	LDHA Inhibitor FX11	Dehydrogenase
	FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 μM. FX-11 can activate PKM2 (pyruvate kinase M2). FX-11 can reduce ATP levels, induce...		Dehydrogenase
T3175	LDHA-IN-4	AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase
	LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 μM.		Dehydrogenase
T39805	LDHA-IN-3	PSTMB,1-(phenylseleno)-4-(trifluoromethyl) benzene	Dehydrogenase
	LDHA-IN-3 (1-(phenylseleno)-4-(trifluoromethyl) benzene) is a potent non-competitive lactate dehydrogenase (LDHA) inhibitor with an IC50 value of 145.2 nM.LDHA-IN-3 is a selenobenzene compound that can be used in cancer ...		Dehydrogenase
T15435	GSK2837808A		Dehydrogenase
	GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).		Dehydrogenase
T4295	(R)-GNE-140	GNE-140	Dehydrogenase
	(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.		Dehydrogenase
T11829	LDH-IN-1		Dehydrogenase
	LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).		Dehydrogenase
T19831	Sodium Oxamate	oxamate sodium,Oxamic acid sodium salt,Aminooxoacetic acid sodium salt,SO	Apoptosis , Dehydrogenase , CDK
	Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA. Sodium Oxamate has antitumor activity and induces cell cycle arrest and apoptosis.		Apoptosis , Dehydrogenase , CDK
T24530	NHI-2	NHI 2
	NHI-2 is an inhibitor of LDHA that acts by reducing lactate production in HeLa cells.
T27421	GNE-140 racemic	GNE-140,GNE 140,GNE140
	GNE-140 racemic is a potent lactate dehydrogenase (LDHA) inhibitor.
T73222	LDHA-IN-5
	LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary hyperoxaluria.
T60995	LDHA/PDKs-IN-2
	LDHA/PDKs-IN-2 (compound 20k) is a potent LDHA and PDKs dual inhibitor with IC50 values of 0.7 and 1.6 μM, respectively. LDHA/PDKs-IN-2 increases oxygen consumption as well as decreases the lactate formation. LDHA/PDKs-I...
T13450L	GNE-140 racemate	GNE-140 (racemate)	Others
	GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.		Others
T61339	LDHA/PDKs-IN-1
	LDHA/PDKs-IN-1 (compound 20e) is a highly effective dual inhibitor of PDKs and LDHA, displaying IC50 values of 0.8 μM and 0.15 μM, respectively. It significantly suppresses A549 cell proliferation (EC50 = 13.2 μM), reduc...
T79874	CHK-336
	CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria research [1].
T79204	Anticancer agent 122
	Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use in cancer research [1].